Regenerative medicine holds incredible promise for stroke survivors like Jian. But before his stroke, Jian developed other health conditions which could complicate using his own cells for therapy. Here's how StemFreeze could have helped Jian:
Jian stores his healthy stem cells in his early 30s using the StemFreeze service, halting the aging process for his stored cells.
Jian's stored stem cells remain frozen in time in our secured partner location. While Jian's other cells undergo changes and mutations from daily life, Jian's banked cells remain the same as when he was 30.
Jian develops Chronic Lymphocytic Leukemia, a slowly progressing form of leukemia, due to aging and mutations in his marrow cells.
Unknown to Jian, also he develops atrial fibrillation (afib), which puts him at increased risk of stroke and heart failure. His afib has not symptoms and is not diagnosed at this time.
Jian suffers but survives two minor strokes, caused by his underlying afib. The strokes cause damage to his brain that his body cannot repair on its own, however his stem cells have CLL and are not suitable for cell therapy.
Fortunately, Jian has access to the stem cells of his 30 year old self, before developing CLL. These younger, healthier, stem cells can be used in cutting edge therapies to help repair the damage from his stroke.
Jian and Silene cofounder, Alex - father and son
Research has shown that our stem cells age with us, and importantly, that stem cell aging may be a major driver of aging-related diseases and cancer - the very diseases we intend to use our stem cells to treat.
New DNA mutations each time our stem cells divide1
Age when mutations affecting stem cell function become more frequent2
Percentage of people age 70+ that may have compromised stem cell function3
1. Holstege H. (2014) Genome Research.
2. Adams PD. (2015) Cell Stem Cell.
3. Genovese G. (2015) New England Journal of Medicine.
Many factors can accelerate the speed at which our bodies and stem cells age - but aging is a one way street, and there's no going back.
Stressed? Lack of sleep and chronic stress causes accelerated aging.
Exposure to dirty air, certain chemicals, or even the sun increases the risk of cellular mutations.
What you eat may affect the rate at which your cells accumulate mutations, including alcohol consumption.
Family history can be a strong indicator of risk of certain diseases.